Abstract
The action of chlorpromazine, serotonin and prostaglandin F2-alpha on the cellular membrane potential of 2-cell mouse embryos, as well as a protective effect of serotonin and prostaglandin F2-alpha against the inhibition of the membrane potential by chlorpromazine were studied. Chlorporomazine (1.10-5 g/ml) proved to induce a strong decrease of the membrane potential, but serotonin, prostaglandin F2-alpha were ineffective. Serotonin (1.10-4 g/ml) prevented the action of chlorpormazine (2.10-6 g/ml), whereas prostaglandin F2-alpha (4-8.10-6 g/ml) was ineffective in this respect.
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