Abstract
We investigated the effect of resveratrol on reproductive toxicity induced by Bisphenol A (BPA) in male mice. Forty mice were randomly classified into five groups: Control; Bisphenol A; Bisphenol A + Resveratrol; Resveratrol and vehicle. Histological alterations, oxidative stress markers, and sperm parameters were examined. BPA caused an evident decrease in sperm motility, count, viability, and oxidative stress markers (p < 0.05). Also, the increase in malondialdehyde, tissue damage, and abnormal sperm observed in the BPA group (p < 0.05) while the treatment of resveratrol significantly increased the above disarrays (p < 0.05). Overall, we reported that resveratrol reduces negative effects caused by BPA in spermatogenesis.
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