Abstract
Protective effect of placental mesenchymal stem cells on histological changes of pancreas experimentally induced by alloxane in mice
Highlights
For the past few years, in an attempt to find new sources of cells that may be used in cell therapy numerous researchers have highlighted the particular properties of mesenchymal stem cells [1,2,3,4]
This study focuses on placental mesenchymal stem cells (PMSCs) in an attempt to differentiate them in vivo into islets of Langerhans in order to treat the diabetes mellitus
In this study we induced diabetes mellitus by alloxan an diabetic agent by injecting the mice with 70 mg/kg body weight and all the mice were found to be diabetic after 72 hours. this result is similar to that recorded by [9,17] who use the same diabetic agent other authors use another diabetic agent Streptozotocin and obtained the same result by Phuc et al [18] and we can detect induce the diabetes in the mice by measuring the blood sugar level by using strips
Summary
For the past few years, in an attempt to find new sources of cells that may be used in cell therapy numerous researchers have highlighted the particular properties of mesenchymal stem cells [1,2,3,4]. Protective effect of placental mesenchymal stem cells on histological changes of pancreas experimentally induced by alloxane in mice
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