Abstract
MOST of the radiobiological protection substances reported in the past are effective when they are administered during, or just before, irradiation, or when given in seriously toxic doses. Therefore, they are of little value for practical purposes except such a case as will be expected preliminarily in medical irradiation. The ideal radiobiological protection substance should give longer tolerance to radiation as in the case of an ideal agent against infectious disease—vaccine. Betz1 and Cronkite et al.2 have reported the change of the effects of whole-body pre-X-irradiation resulted in a reduced mortality rate in mice. But this previous irradiation should be avoided in consideration of cumulative genetic effect of radiation. We have adopted the inhalation of ozone of relatively low concentration as a previously administrative agent for radiation protection. Ozone is well known as radiomimetic3, but neither a leucopenia nor the existence of ozone was determined in the blood of the mice exposed in a relatively low concentration of ozone.
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