Abstract
In the current study, we examined the effect of Morinda officinalis polysaccharides (MOP) on bone quality in aged rats. Rats were given orally by daily gavage at 200 and 400 mg/kg/day for 3 months, respectively. The results showed that there was a significant decrease in serum alkaline phosphatase (ALP), Interleukin 6 (IL-6) content and a significant increase in density and strength of femur and lumbar vertebrae in aged rats 3 months afterMorinda officinalis polysaccharides treatment. In conclusion, these data suggest thatMorinda officinalis polysaccharides can protect the age-induced bone degeneration. Key words: Morinda officinalis polysaccharides, bone, osteoporosis, ALP.
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