Abstract

The aim of this study was to investigate the effect of laminarin polysaccharides (LP) on exhaustive exercise-induced oxidative stress in rats. A total of thirty-two rats were randomly divided into the following four groups: Sedentary control group (C), exhaustive exercise group (E), LP treatment group (L) and exercise group subjected to exhaustive exercise and LP treatment (EL). Rats in the L and EL group received supplemental LP diet (300 mg/kg body weight) for 30 consecutive days, and rats in C and E groups received the same volume of 0.9% NaCl for the same days as rats in the L and EL group. Rats in the E and EL group underwent 30 day exhaustive exercise experiments on a treadmill. Blood and skeletal muscle were collected. The biochemical markers in serum were determined and the level of lipid peroxidation and antioxidants in muscle were measured. Exhaustive exercise caused elevations of biochemical markers and lipid peroxidation (P<0.05) and decreases of antioxidants (P<0.05). The presence of LP with exhaustive exercise significantly decreases the blood biochemical markers and lipid peroxidation (P<0.05) and significantly increased the levels of the antioxidants in muscle (P<0.05). Our results indicate that LP could be a potent protective agent against exhaustive exercise-induced biochemical alteration and oxidative stress in rats. Key words: Antioxidant activity, polysaccharides, animal models, exercise.

Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call