Abstract
Abstract The inhibition effect of selected amphiphilic quaternary alkyl-substituted ammonium salts on oxidation of the lecithin liposome membrane was studied, induced by ultraviolet light and Fe2+ ions with ascorbic acid added. The salts differed in alkyl chain length Ri having the following alkyl substitutents: R1 = C9H19; R2 = C10H21; R3 = C12H25; R4 = CH2OC14H29; R5 = CH2OC16H33. It was found that all the salts used induced inhibition in oxidation of the liposome membrane, both that induced by UV light and ferrous ions. The antioxidant activity of the salts studied, dependent on the chain length and concentration, can be represented by the relation R1 < R2< R3 < R4 < R5. A similar dependence was obtained when the hemolytic activity of compounds was studied. Activity of salts increase with alkyl chain length.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
