Abstract
Salvianolic radix, one of the most commonly used traditional Chinese herbs, was widely studied about its actions against liver injury and fibrosis, and was one of the focuses of recent research[1,2]. Salvianolic acid-A (SA-A) was an aqueous soluble component of Salvianolic radix. In our previous work[2], SA-A was found to have protective effects against liver injury and fibrosis induced by carbon tetrachloride (CCl4) in rats. In order to investigate the effect of SA-A on peroxidation in hepatocytes, we induced the injured hepatocyte model by CCl4 fumigation in vitro, treated the cell model with SA-A or aqueous soluble vitamin E (Vitamin E), the latter served as the control drug, and observed the influences of the drugs on the functions of the hepatocytes injured by peroxidation.
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