Abstract
Summary: Ca2+ protected yeast ceJls very effectively against the toxic effects of Cd2+; Mg2+had only a slight protecting effect as far as protection against Cd2+-induced release of K+ was concerned. Protection of the yeast cells against Cd2+ toxicity was due to a reduction in Cd2+ uptake in the presence of Ca2+. A single relationship existed between the relative rate of K+ release induced by Cd2+ and the cellular Cd2+concentration. Within the first few minutes of incubating cells with Cd2+. the molar ratio of K+ released and Cd2+ accumulated was 22 and was independent of the amount of CdC12 added. This ratio decreased during incubation of the cells with Cd2+. depending on the external Cd2+concentration.
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