Abstract
Poly (sodium 4-styrenesulfonate) (PSS) was used to synthesize biocompatible inorganic calcium carbonate (CaCO 3) microspheres. The influence of different functional group unit molar ratios of [PSS]/[Ca 2+] to the morphology and crystal phases of CaCO 3 microspheres was studied by high scan electrode microscope (HSEM) and X-ray diffraction. These synthesized microspheres were used as the template of microcapsules. Protamine (PRM) and dextran sulfate (DXS) were self-assembled on the surface of the obtained microshperes alternatively for six layers. After the CaCO 3 was dissolved the microcapsules were obtained, which were characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM) and TGA. This kind of biocompatible microcapsules could be used as micro-containers to load drugs and micro-reactors to perform chemical reactions.
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