Abstract
BackgroundX-linked hypophosphatemia is associated with a range of dental problems, many of which may result in early loss of the dentition. Most patients, but especially young adults, are likely to desire fixed prosthodontic replacements, and dental implants may be the preferred solution in many cases. The use of dental implants to rehabilitate this patient group has not been widely studied with the literature limited to a small number of case reports with limited follow-up.Case presentationThis case report describes the dental journey of a young adult with X-linked hypophosphatemia, his eventual tooth loss and rehabilitation with multiple dental implants. Over 10 years’ follow-up of three of the fixtures is presented.ConclusionsThis case report shows a common presentation and progression of a patient with X-linked hypophosphatemia and will hopefully provide further positive evidence for the clinician to rely on when considering dental implant based treatments for such patients.
Highlights
X-linked hypophosphatemia is associated with a range of dental problems, many of which may result in early loss of the dentition
The genetic mutation is of the phosphate-regulating gene PHEX which results in reduced phosphate reabsorption by the kidneys [3] and due to the dependency between calcium and phosphate homeostasis results in bone deformities, bone pain, reduced growth, hypophosphatemia, inappropriately normal serum 1,25(OH)2D levels and phosphate wasting [4]
There is a general lack of information about X-linked hypophosphatemia (XLH) and treatment guidelines which frequently lead to missed diagnoses and mismanagement [5]
Summary
This case report shows a common presentation and progression of a patient with X-linked hypophosphatemia and will hopefully provide further positive evidence for the clinician to rely on when considering dental implant based treatments for such patients.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
