Abstract
OBJECTIVE. The authors assessed an impact of the design of biological prosthesis on efficacy of aortic valve replacement in elderly patients. MATERIAL AND METHODS. Randomized parallel controlled prospective study was carried out. The patients were divided into groups with stented and stentless prostheses. A value of peak valve gradient was determined as a primary end point. RESULTS. The peak gradients were significantly higher in the first group than in the second group. There was noted a significant difference in value of miocardial hypertrophy of the left ventricular (mass index of the myocardium) during 30-day terms after operation. CONCLUSIONS. The final results would be possible to consider after the end of the study. The results of intermediate analysis supported the validity of the proposed hypothesis.
Highlights
The authors assessed an impact of the design of biological prosthesis on efficacy of aortic valve replacement in elderly patients
There was noted a significant difference in value of miocardial hypertrophy of the left ventricular during 30-day terms after operation
Изучив результаты наблюдения за пациентами в течение 1 года после операции, мы сможем окончательно сформировать мнение о влиянии типа протеза на качество жизни пациентов, гемодинамические характеристики, выживаемость и наличие или отсутствие осложнений
Summary
I. Semenova Prosthesis of aortic valve by stented and stentless biological prostheses: intermediate analysis of results E. Разница в величине гипертрофии миокарда левого желудочка (индекс массы миокарда) достоверна (р = 0,007), но окончательные выводы можно будет сделать только после полного завершения исследования (обследование всех пациентов через 1 год после операции). Несмотря на больший размер имплантированных бескаркасных клапанов, через 8 нед после операции авторы не выявили разницы в величинах транспротезного градиента давления и массы миокарда левого желудочка.
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