Abstract

IntroductionParacoccidioidomycosis is a systemic mycosis in Latin America that can affect various organs. Few case reports of paracoccidioidomycosis affecting the prostate are found in the literature.Case presentationWe present the case of a 79-year-old Caucasian man with a six-month history of irritative symptoms of the prostate (urgency, frequency and nocturia) and difficulty initiating urination that progressed to urinary retention and the use of a urinary catheter. The anatomopathological analysis of the transurethral resection of the prostate revealed chronic granulomatous prostatitis of fungal etiology (paracoccidioidomycosis) with extensive necrosis. The patient began treatment with itraconazole at a dose of 100mg/day for six months. Radiography of the thorax revealed bilaterally diffuse nodular reticular interstitial lesions. The patient progressed to respiratory failure and was sent to the intensive care unit, but suffered a cardiopulmonary arrest and was pronounced dead.ConclusionsDue to the high incidence of paracoccidioidomycosis in countries like Brazil, urologists should suspect blastomycosis in all patients with symptoms of lower urinary obstruction with chronic abacterial prostatitis. Considering that paracoccidioidomycosis has the potential to affect various organs, following diagnosis, the treatment must be initiated as soon as possible.

Highlights

  • Paracoccidioidomycosis is a systemic mycosis in Latin America that can affect various organs

  • PCM is caused by a dimorphic fungus denominated Paracoccidioides brasiliensis and transmitted by means of the inhalation of spores through the respiratory system

  • Case presentation We present the case of a 79-year-old Caucasian male field worker from the state of São Paulo (Brazil) with a six-month history of irritative symptoms of the prostate and difficulty initiating de Arruda et al Journal of Medical Case Reports 2013, 7:126 http://www.jmedicalcasereports.com/content/7/1/126 urination that progressed to urinary retention and the use of a urinary catheter

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Summary

Introduction

Paracoccidioidomycosis is a systemic mycosis in Latin America that can affect various organs. Few case reports of paracoccidioidomycosis affecting the prostate are found in the literature. The anatomopathological analysis of the transurethral resection of the prostate revealed chronic granulomatous prostatitis of fungal etiology (paracoccidioidomycosis) with extensive necrosis. The patient progressed to respiratory failure and was sent to the intensive care unit, but suffered a cardiopulmonary arrest and was pronounced dead. Paracoccidioidomycosis (South American blastomycosis) is a systemic mycosis in Latin America. Paracoccidioidomycosis (PCM) mainly affects male individuals between 30 and 60 years of age, with rare occurrences in individuals under 14 years of age. The most common agents of fungal prostatitis are Candida albicans, Aspergillus sp., Cryptococcus neoformans and Blastomyces dermatitidis, affecting mainly immunodepressed patients [1]

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