Abstract
1. 1. The presence of tyrosine hydroxylase, monoamine oxidase and catechol- O-methyltransferase as well as the putative transmitters, dopamine, 5-hydroxytryptamine and its metabolite, 5-hydroxyindoleacetic acid, has been demonstrated in the methylcholantherene-induced prostatic carcinoma of rats. 2. 2. Although norepinephrine was present in the normal ventral prostate, it was non-detectable in the epithelial cells of neoplastic prostate. 3. 3. Castration of rats implanted with tumour cells significantly reduced the activity of tyrosine hydroxylase, transmitters and the metabolite, 5-hydroxyindoleacetic acid suggesting that the metabolism of these monoamines is androgen-dependent.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
