Abstract
A 47-year-old Greek diabetic man presented with erectile dysfunction and a decrease in sexual desire. The patient had type 2 diabetes for the previous 8 years and was on treatment with rosiglitazone and metformin with strict glycemic control (HbA1c 5.8%). No symptoms or signs of neuropathy were present. Hypogonadotrophic hypogonadism was found. His plasma testosterone level was very low (100 ng/dl [reference range 300–1,000]) and there was no luetinizing hormone response to luetinizing hormone–releasing hormone (LHRH) test. Further work-up with a magnetic resonance imaging scan and hypophyseal function tests did not reveal any space-occupying lesions of the hypothalamic pituitary site. The process led to the diagnosis of idiopathic hypogonadotropic hypogonadism. On further work-up, the patient was found to have a prostatic carcinoma. …
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