Prostate leiomyosarcoma: A rare tumor

I Benali I Benali,M Allaoui M Allaoui,A Mejdoubi A Mejdoubi

doi:10.30574/gscarr.2021.9.2.0257

Abstract

Leiomyosarcoma is a rare neoplasm with a poor survival rate. Between June 2018 to January 2019 we treated a rare case of Prostate Leiomyosarcoma initially metastatic to the lung and the liver with multiple pelviclymph nodes. Five cycles of chemotherapy and palliative radiotherapy have been delivered with a mean follow up of 1 year .Chestabdominal-pelvic CT scan with MRI and bone scan are necessarily to assess clinical staging. The objective of this study is to review our experience in the management of Prostate Leiomyosarcoma at the Casablanca Cancer Center of Mohammed VI University of Health Sciences with a literature review of this rare neoplasm.

Highlights

Prostatic leiomyosarcoma is a rare primary tumor in adults representing 38% to 52% of primary prostate sarcomas that accounts for less than 0, 1% of prostate malignancies
Between June 2018 to January 2019 we treated a rare case of Prostate Leiomyosarcoma initially metastatic to the lung and the liver with multiple pelviclymph nodes
The objective of this study is to review our experience in the management of Prostate Leiomyosarcoma at the Casablanca Cancer Center of Mohammed VI University of Health Sciences with a literature review of this rare neoplasm

Summary

Introduction

Prostatic leiomyosarcoma is a rare primary tumor in adults representing 38% to 52% of primary prostate sarcomas that accounts for less than 0, 1% of prostate malignancies. Chestabdominal-pelvic CT scan with MRI and bone scan are necessarily to assess clinical staging .The aim of this work is to present a rare case of Prostatic Leiomyosarcoma treated with chemotherapy and decompressive analgesic radiotherapy with a literature review regarding the clinical features, diagnostic modalities and therapeutic aspects of this rare entity. A 40-year-old male patient, without medical or surgical history of interest. He has presented since March 2017 rectal pain tension and burning with urination. On further evaluation with Chestabdominal-pelvic CT scan ( figure 1- figure 2- figure 3 ) it was seen that this large heterogeneous mass of the prostate presented irregular contours with area of infiltration of the bladder base and anterior rectal wall. After the multidisciplinary meeting the patient received palliative radiotherapy with a total dose of 30Gy on 10 fractions five days per a week, on oncology hospitalization he had undergone 5 cycles of Corresponding author: I Benali Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco

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