PROSTATE CANCER DETECTION USING HISTOPATHOLOGY IMAGES AND CLASSIFICATION USING IMPROVED RideNN

Abstract

Medical industry reports prostate cancer as common and high among men and alarms the necessity for detecting prostate cancer for which the required morphology is extracted from the histopathology images. Commonly, the Gleason grading system remains a perfect factor for grading prostate cancer in men, but pathologists suffer from minute inter- and intra-observer variations. Thus, an automatic method for segmenting and classifying prostate cancer is modeled in this paper. The significance of the developed method is that the segmentation and classification are gland-oriented using the Color Space (CS) transformation and Salp Swarm Optimization Algorithm-based Rider Neural Network (SSA-RideNN). The gland region is considered as the morphology for cancer detection from which the maximal significant regions are extracted as features using multiple-kernel scale-invariant feature transform (MK-SIFT). Here, the RideNN classifier is trained optimally using the proposed Salp–Rider Algorithm (SRA), which is the integration of Salp Swarm Optimization Algorithm (SSA) and Rider Optimization Algorithm (ROA). The experimentation is performed using the histopathology images and the analysis based on sensitivity, accuracy, and specificity reveals that the proposed prostate cancer detection method acquired the maximal accuracy, sensitivity, and specificity of 0.8966, 0.8919, and 0.8596, respectively.