Abstract
We report two cases of seed migration to the ischial bone after prostate brachytherapy. A 78-year-old male and a 66-year-old male underwent transperineal interstitial permanent prostate brachytherapy with loose 125 I seeds. Postimplant pelvic radiographs revealed a seed that was overlapped by the right ischial bone. Postimplant pelvic computed tomography revealed a seed that migrated to the right ischial bone. The two cases had no symptoms related to the migrated seed. This is the first report of seed migration to the ischial bone after transperineal interstitial permanent prostate brachytherapy. For these two cases, it is hypothesized that the seeds migrated to the ischial bone via the pelvic venous pathway, not via the systemic circulation.
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