Abstract
Cloprostenol is a synthetic prostaglandin F analogue. It is a FP (Prostaglandin F) receptor agonist, which shows 2· powerful luteolytic effects. It also stimulates the contraction of uterine and bronchial smooth muscle and produces vasoconstriction in some vessels. Anoestrous may be due to some conditions like abnormal pregnancy, early pregnancy, pyometra, endometritis, retention of placenta, maceration and mummification. So, get rid of this conditions cloprostenol is widely used. It has been now in vogue to administer PGF or its analogue in early 2· postpartum cows and buffaloes in order to hasten early resumption of cyclic ovarian activity and thereby to increase the reproductive efficiency. To improve reproductive efficiency, it is necessary to inseminate cows early in the breeding season so that, thereby achieving a more compact calving season. Breeding efficiency is increased by means of synchronization of estrus, conception rate and pregnancy rate. Estrus synchronization can be achieved by lysis of corpus luteum by administration of prostaglandin (PGF ) or its synthetic analogue on 5-17 2· days of the estrus cycle. The cows will return to estrus within 3-5 days. The effective therapeutic doses for cloprostenol are 500 µg in cattle and 175 µg in pigs. However, for R-cloprostenol, the recommended doses are: 150 µg in cattle and 75 µg in pigs. In both cases, it is administered by the intramuscular route.
Highlights
The successful economics of a dairy farm production lies in ensuing proper and optimal reproductive rhythm of each individual cow and buffaloes in the herd, within the normal physiological range
Fertility and breeding efficiency of dairy animals plays a pivotal role in dairy economics
Bacterial infection is the most important among the various causes of the sub-fertility [4]. Such a condition may cause cervicitis or endometritis of various degrees, which in turn may lead to embryonic death and repeat breeding problems [5]
Summary
The successful economics of a dairy farm production lies in ensuing proper and optimal reproductive rhythm of each individual cow and buffaloes in the herd, within the normal physiological range. Bacterial infection is the most important among the various causes of the sub-fertility [4] Such a condition may cause cervicitis or endometritis of various degrees, which in turn may lead to embryonic death and repeat breeding problems [5]. These infections affect fertility by altering the uterine environment, resulting in impairment of sperm transport, sperm death and hostile environment to the subsequent development and maintenance of the conceptus leading to early embryonic death. Delayed uterine clearance which leads to retention of placenta and subsequent development of anoestrus condition, reduced breeding efficiency, endometritis and pyometra are major problems contributing to subfertility and infertility in farm animals. This essay will illustrate the role of cloprostenol in anoestrus and to improve breeding efficiency
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
