Abstract
A group of 10 patients, with pregnancies of varying gestational age, complicated by missed abortion, intra-uterine death, anencephaly and chromosomal anomaly, underwent induction of labor by intra-amniotic prostaglandin F 2α infusion. Induction of labor was successful in all cases and the side-effects were mild. The induction-delivery interval did not differ significantly from that recorded when labor in such cases has been induced by intravenous PGF 2α. The induction-delivery interval showed no apparent relation to the state of the fetus (living or dead) suggesting that no significantly active role is mediated by the fetus in PGF 2α-induced labor.
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