Abstract
Prostaglandin E2 (PGE2) plays an important role in modulating microglial function. In the present study, we have found that PGE2 increases expression of mRNA for cyclooxygenase-2 (COX-2) and microsomal prostaglandin E synthase-1 (mPGES-1), which are involved in PGE2 synthase in cultured rat microglia.
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