Prospects for the application of lignin containing sorbents in veterinary medicine

Abstract

Vaccines against colibacillosis are mainly used, containing only one specific variant of pathogenic E. coli with a preventive purpose among the livestock of stationary dysfunctional farms in conditions of Krasnoyarsk region. For therapeutic purposes, veterinarians usually use wide range of antimicrobial preparations to combat outbreaks of gastrointestinal infections. Many researchers point to the high variability of E. coli bacteria. Use of such preparations, in addition to the formation of high resistance in opportunistic microorganisms to the latter, provoke the accumulation of antibacterial drugs in animal products. Authors conducted studies of the possibility of the practical use of lignin-containing sorbents for therapeutic and prophylactic purposes in field of veterinary medicine in the period from 2001 to 2020. Authors proposed to use the residues after extraction, formed during the complex processing of larch bark, as an enterosorbent. Authors studied the therapeutic and prophylactic effect of enterosorbent from larch bark in case of gastrointestinal infections in experiments in vivo. It was found that the use of the sorbent for therapeutic purposes for 2 days ensured the safety of laboratory animals in the acute form of colibacillosis infection. Preservation was ensured by preventing the penetration of microbial toxins into the tissues of the gastrointestinal tract. The prophylactic and therapeutic efficacy of the investigated type of enterosorbent is associated with angioprotective, antitoxic effects due to the high sorption capacity of the drugs.