Abstract
Introduction. Frequently and long-term ill children are an urgent problem in pediatrics. It is of interest to take into account the possibility of rehabilitation of frequently and long-term ill children using the natural resources of the region.Objective. To study the clinical and immunological parameters of children -residents of the Altai Territory, who are often prone to acute respiratory diseases, and the effect on these indicators of herbal tea from the shoots of Pentaphylloides fruticosa, used in complex therapy and rehabilitation of frequently and long-term ill children.Materials and methods. The study involved 49 children aged 3.5 to 7 years of both sexes, who are in the dispensary group of frequently and long-term ill children. During the study, a retrospective analysis of primary medical documentation was carried out, as well as a comprehensive clinical and laboratory, microbiological and parasitological examination, and determination of the immune status. In a prospective cohort study, the effect of the use of herbal tea from the shoots of Pentaphylloides fruticosa on the clinical and immunological parameters of frequently and long-term ill children was evaluated as part of complex therapy with bacterial lysates and endogenous interferon inducers.Results. The age-sex structure of frequently and long-term ill children is dominated by children of preschool age (up to 70%), mostly males (53%), who have a burdened anamnesis (31%). Frequent episodes of respiratory diseases are not a consequence of immune deficiency and develop against the background of an associated, persistent viral and bacterial infection that occurs against the background of transient functional instability of the immune system. The quantitative analysis of immunograms showed a significant immunocorrective role of Pentaphylloides fruticosa extraction preparations in comparison with baseline values.Conclusions. The conducted clinical and immunological study did not reveal any significant clinically significant disorders of the immune system in frequently and long-term ill children -residents of the Altai Territory. At the same time, the use of extractive preparations of Pentaphylloides fruticosa has a significant immunocorrective effect on the parameters of the immune system and can be considered as an important component in the complex rehabilitation of frequently and long-term ill children from the age of 3.5 years.
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