Abstract

Precision medicine emphasizes treatments targeted to the needs of individual patients on the basis of genetic, biomarker, phenotypic, or psychosocial characteristics that distinguish a given patient from other patients with similar clinical presentations. Inherited ocular diseases are among the leading causes of blindness. This highly heterogeneous group of diseases poses significant therapeutic challenge. Achieving the goals of precision medicine by application of next-generation sequencing, gene-therapy, iPSCs and CRISPR/Cas9 may be feasible in the near future, which will play important roles in the field of inherited ocular diseases. Key words: Eye-diseases, hereditary; Gene therapy; Precision medicine; Next-generation sequencing; CRISPR/Cas9

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