Abstract
Hypertension in pregnancy is a big threat to the mother as well as the fetus. Predi³³ction of preeclampsia with reasonable accuracy is one of the essential prerequisites for its prevention. Various biological markers are available for the prediction of preeclampsia but none of those is reasonably reliable, valid and economical. In this present study, the predictive value of the urinary calcium-creatinine ratio (CCR) for the prediction of preeclampsia was studied. This study was conducted at department of Obstetrics and Gynaecology, Sir T Hospital, Government Medical college, Bhavnagar. 500 Primigravida patients attending the antenatal outpatient department at Sir T Hospital between 18 to 24 weeks of gestation were registered in this study. Single voided urine sample was collected from all the patients in calcium free vial for estimation of urine calcium and creatinine. After initial workup, all patients were followed in the antenatal clinic till the time of delivery and 15 days post partum. The number of patients who develop the hypertensive disorder in pregnancy was noted and the correlation studied. Out of 500 patients, 120 patients (24%)developed preeclampsia,4 patients(0.8%)developed eclampsia,10 patients (2%) developed gestational hypertension. Out of 500 patients, 84 patients (16.8%) showed UCCR<0.04.The remaining 416 patients (83.2%) showed UCCR>0.04. Out of 84 patients with UCCR<0.04, 2 patients (2.38%) developed Gestational Hypertension. : A single estimation of calcium to creatinine ratio in asymptomatic pregnant women between 18-24 week of gestation is a simple and cost-effective test. A value of less than or equal to 0.04, in a spot urine sample, has a good predictive value for preeclampsia
 Keywords: Calcium creatinine ratio, Gestational hypertension, Preeclampsia, Preeclampsia prediction
Highlights
Hypertension can occur in normotensive pregnant women or can aggravate already existing hypertension
Out of 500 patients, 120 patients (24%) developed preeclampsia,4 patients(0.8%)developed eclampsia,10 patients (2%) developed gestational hypertension
Calcium-to-creatinine ratio has been suggested by many to be a good screening test for preeclampsia [3]. in study, urine calcium creatinine ratio (UCCR) is tested as parameters to predict the development of preeclampsia in asymptomatic normotensive primigravida women
Summary
Hypertension can occur in normotensive pregnant women or can aggravate already existing hypertension. Hypertensive disorders represent the most common medical complications of pregnancy. Hypertensive disorders occur in 5–10 % of all pregnancies [1] They contribute to significant maternal and perinatal morbidity and mortality of which 3.9% is preeclampsia. By identifying the pregnant women who are destined to develop gestational hypertension, in order to avoid dangerous complications is the aim of various researchers and this lead to the interest in screening. Combining the biochemical markers calcium, creatinine, and microalbuminuria, we can predict the risk of disorder and start preventive therapy at early stages to prevent maternal and feto-neonatal morbidity and mortality.[4,5]An early diagnosis and treatment helps to International Journal of Medical and Biomedical Studies (IJMBS)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Medical and Biomedical Studies
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
