Abstract
It is often difficult for the examining finger in the rectum to decide whether the enlargement is due to benign or malignant or inflammatory conditions of the prostate such as chronic inflammation, both specific and nonspecific prostatic abscess, calculi, benign hyperplasia and carcinoma of prostate. Prostatic obstruction must be diagnosed as early as possible so that definite treatment can be instituted prevent the sequele of the obstruction. Determination of histological nature of lesion is the only positive method of establishing a definitive diagnosis. A suitable and simple technique of obtaining biopsy material and aspirational material from prostate for definitive diagnosis is essential. Aim of this study was Comparision between Trucut biopsy and FNAC in lesions of prostate gland. A prospective comparative study of Trucut biopsy vs FNAC of prostate in patient with prostate specific antigen > 4 ng/ml, was conducted among 50 patient. Patients were chosen for the study on the basis of clinical history and DRE. Patient with LUTS symptoms and enlarged Prostate on DRE were further subjected to PSA screening through blood examination at pathology lab and ultrasound for measuring prostatic volume at Radiology Department. Following consent, patients are subjected for FNAC and Trucut biopsy under local anaesthesia. Out of 50 patients, by Trucut biopsy diagnosed case of BPH are 30,Ca.Prostate are 5 and chronic prostitis are 5, while by FNAC diagnosed case of BPH are 15 , Ca.prostate are 3 and chronic prostitis are 2. In developing countries like India FNAC is more preferable due to its simplicity ,very low cost and least invasiveness and very less or no complication. Overall present studies suggest that Trucut biopsy is superior to FNAC in diagnosis and management of prostate diseases.
 Keywords: FNAC, Trucut biopsy, Lesions of prostate gland.
Highlights
Prostate cancer continues to be a major public health problem in both industrialized and developing countries worldwide
In 1930, Russell Ferguson reported that prostate cancer could be diagnosed by transperineal fine needle aspiration (FNA); it took three decades before Sixten Franzen developed a trans-rectal approach to prostate biopsy and applied prostate FNA to diagnostic uropathology.[1]The development of a special instrument for prostatic aspiration led to a painless quick method of cytologic sampling of the prostate by trans-rectal FNA biopsy
Both procedure FNAC and Trucut biopsy done in all 50 patients
Summary
Prostate cancer continues to be a major public health problem in both industrialized and developing countries worldwide. Prostate disease is one of the common problem of old age group and third most common cause of cancer death in males. According to the World Health Organization, there are about 2,50,000 new cases of prostatic cancer every year. Cytology and histopathology have been the forefront of cancer detection but how well these two correlate has been a content of debate. In 1930, Russell Ferguson reported that prostate cancer could be diagnosed by transperineal fine needle aspiration (FNA); it took three decades before Sixten Franzen developed a trans-rectal approach to prostate biopsy and applied prostate FNA to diagnostic uropathology.[1]The development of a special instrument for prostatic aspiration led to a painless quick method of cytologic sampling of the prostate by trans-rectal FNA biopsy.
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