Abstract
Objective:To study the efficacy of the enhanced recovery after surgery (ERAS) program on postoperative recovery and complications in patients with gastric cancer.Methods:Eighty patients in the perioperative period with radical gastrectomy were enrolled and randomly divided into 2 groups, the ERAS group and the non-ERAS group. The differences between the 2 groups in terms of postoperative recoveries and complications rate were determined. According to the body mass index (BMI) level, the ERAS group was divided into 2 subgroups, namely group A (BMI < 28 kg/m2, n = 16) and group B (BMI ≥ 28 kg/m2, n = 24). The non-ERAS group was also divided into group C (BMI < 28 kg/m2, n = 18) and group D (BMI ≥ 28 kg/m2, n = 22). The recovery and complications of each group were then determined.Results:The postoperative length of stay and visual analogue scale pain score were less in the ERAS group than the non-ERAS group (P < 0.05). Time to first postoperative exhaustion, first postoperative defecation, returning leukocyte count to normal, and stopping intravenous nutrition were significantly shorter in the ERAS group (n = 40), compared to the non-ERAS group (n = 40, all P < 0.05). The incidence of postoperative lower extremity intramuscular venous thrombosis was significantly higher in group D than in group B (χ2 = 4.800, P = 0.028). In addition, the incidence of lower extremity intermuscular venous thrombosis and lung infection in group D was higher than those in other groups.Conclusions:The perioperative ERAS program was associated with faster recovery in patients undergoing radical gastrectomy. For patients with higher BMI (BMI ≥ 28 kg/m2), the use of the perioperative ERAS program was more advantageous.
Highlights
Enhanced recovery after surgery (ERAS) is a series of evidence-based health management strategies in the peri operative period, which reduces psychological and physical traumatic stress responses, postoperative complications, hospital stay times, risks of readmission, incidences of death, and medical costs[1]
ERAS guidelines are based on the highest quality evidence available and as such require updating on a regular basis[2]
The results showed that use of ERAS during the perioperative period significantly triggered postoperative recovery of patients undergoing gastric cancer surgery (Table 3)
Summary
Enhanced recovery after surgery (ERAS) is a series of evidence-based health management strategies in the peri operative period, which reduces psychological and physical traumatic stress responses, postoperative complications, hospital stay times, risks of readmission, incidences of death, and medical costs[1]. ERAS guidelines are based on the highest quality evidence available and as such require updating on a regular basis[2]. The theory of ERAS has been widely used in surgery[2,3,4,5,6,7,8,9]. It was first proposed by the Danish surgeon, Henrik
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