Prospective Randomized comparison of Off-pump and On-pump Multivessel coronary artery bypasses surgery

Abstract

Aim: To ascertain the non-inferiority of off-pump CABG when compared to on-pump CABG in terms of angiographically assessed graft patency at 3 months. Material & Methods: This Prospective Randomized comparison of Off-pump and On-pump Multivessel coronary artery bypass surgery To Evaluate outcomes and graft patency (PROMOTE patency) trial was conducted in Indira Gandhi Institute of medical Sciences, Patna, Bihar, India over a period of one year. Results: A total of 300 patients were enrolled and were randomly assigned to either off-pump CABG (n = 150 patients) or on pump CABG (n = 150 patients). Of 300 patients, 280 patients at 1 month and 295 patients at 3 months survived and were analyzed for MACCE. The incidence of asymptomatic carotid artery stenosis was 0.66% (1 patient) in off-pump and 0.66% (1 patient) in on-pump group, p = 1.01 in our study. No difference was observed between the groups in terms of index of completeness of revascularization (number of grafts performed divided by number of grafts intended) 0.90 vs. 1.00 (p=0.7).