Prospective observation of early diagnosis and accurate diagnosis of invasive mole by transvaginal ultrasound

Abstract

Objective To explore the characteristics of sonographic patterns of invasive mole (IM), observe specific ultrasonic signs and provide more evidences for early and precise diagnosis of IM. Methods Twenty patients diagnosed with IM at the PUMC Hospital from 2014 January to 2016 January were evaluated by transvaginal ultrasonography. These sonographic dynamic images were observed comprehensively and carefully in order to discover the early ultrasound characteristics and specific ultrasonic representations of IM. Results It was indicated by transvaginal ultrasonography that there were myometrial lesions in 4 patients with diameters less than 2.0 cm, performing as heteroechoic lesions in myometrium with obviously increased and disorder blood flow signals after the curettage of uterine cavity. Meanwhile, the myometrial lesions of 8 patients showed hydropic fluid-filled molar vesicles, representing swollen villi. Conclusions After the curettage of uterine cavity, presentations of the myometrial lesions with abnormally rich blood flow contribute to early diagnosis of IM. And the patterns of myometrial hydropic fluid-filled molar vesicles can play an important role in the accurate diagnosis of IM, and may distinguish it from choriocarcinoma. Key words: Ultrasonography; Hydatidiform mole, invasive; Early diagnosis