Abstract
The review gives the characteristics of the general status of the problem of infection in the zone of surgical intervention including the field of traumatology and orthopaedics. The shortcomings of antibiotic use and methods of their local delivery for surgical and orthopaedic needs are considered. The conception of local use of antibacterial agents and the requirements for the current “ideal” antibacterial agent are given. Classification of the local antibiotic delivery systems on the basis of their physicochemical properties is presented as well as the number of prospective methods for the prevention of microorganisms’ adhesion on the surface of the implanted devices and systems that could be used in traumatology and orthopaedics are examined.
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