Abstract
SEVERAL STUDIES have indicated that clinical and radiographic findings fail to distinguish precisely neonates with early onset group B streptococcal septicemia from those with hyaline membrane disease or transient tachypnea of the newborn infant. I-:' Although countercurrent immunoelectrophoresis for the detection of bacterial antigen in body fluids has been shown to be useful for the rapid diagnosis of several bacterial infections, its value for the prospective diagnosis of early onset group B streptococcal disease has not been investigated. This study documents the utility of CIE for the rapid and specific diagnosis of GBS septicemia among infants admitted to high-risk newborn nurseries.
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