Abstract
Indralupta (Alopecia Areata) is not life threatening disorder but it definitely affects the quality of life like impairing psychological well-being thus affecting mental and social status of person due to bald patch. It is characterized by smooth, circumscribed bald patch on the hair bearing area. The risk of allopathic treatment outweighs their benefits. Indralupta is considered under Kshudraroga by most of the authors of classical Ayurvedic texts. Safety and efficacy of Dravanti beeja lepa in regeneration of hair in Indralupta is assessed through present study. Prospective open randomized single-arm clinical trial was carried out on 30 patients showing classical symptoms of Indralupta. A Skin patch test has been done prior to apply the lepa for safety assessment. The Dravanti beeja lepa was given for local application twice a day over a period of 28 day. Indralupta was found to be more prevelant in males. Intake of Amla, Katu and lavana Rasa, non-vegetarian diet, stress factor and use of cosmetics could be considered as etiological factor of Indralupta. On regular use of Dravanti beeja lepa, regeneration of hair was also observed to significant level. Thus, Dravanti beeja lepa proved its safety and efficacy for topical application.
Highlights
Hair form an important anatomical structure of the body, derived from ectoderm of skin, which have protective function and adds beauty to the face
Hair is made up of protein called keratin produced in hair follicles in the outer layer of skin
Alopecia Areata (AA) is a common form of non- scarring alopecia involving the scalp and/ or body, characterized by hair loss without any clinical inflammatory signs. It is one of the most common forms of hair loss seen by dermatologists and accounts for 25% of all the alopecia cases.[2]
Summary
Hair form an important anatomical structure of the body, derived from ectoderm of skin, which have protective function and adds beauty to the face. Alopecia Areata (AA) is a common form of non- scarring alopecia involving the scalp and/ or body, characterized by hair loss without any clinical inflammatory signs. It is one of the most common forms of hair loss seen by dermatologists and accounts for 25% of all the alopecia cases.[2] It was first described by Cornelius Celsus, and the term AA was coined by Sauvages in 1760.3It accounts for 2-3% of the new dermatology cases in UK and USA, 3.8% in China, and 0.7% in India.[3,4,5] In Ayurveda, hair problem described under the broad heading of KshudraRoga[6], Kapala Rogas[7] as Khalitya, Palitya, Indralupta. To assess the safety of Dravanti beeja lepa a skin patch test[12] has been done prior to apply and its efficacy was observed on patients of Indralupt (Alopecia)
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