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Abstract
Propranolol plasma levels and pharmacokinetics (PK) may be altered by cardiopulmonary bypass (CPB). Propranolol kinetic disposition was investigated in patients submitted to myocardial revascularization with mild hypothermic cardiopulmonary bypass (HCPB).
Highlights
Propranolol plasma levels and pharmacokinetics (PK) may be altered by cardiopulmonary bypass (CPB)
Analysis of data from a retrospective study of long distance aeromedical transports performed by Montreal-based Skyservice Lifeguard transport service. (A manuscript describing this study has been accepted for publication in the journal Aviation, Space, and Environmental Medicine.) For patients transported by Lear Jet air ambulance post myocardial infarction (MI), potential risk factors examined included age, gender, Killip class, revascularization procedures, and status at time of transportation
TST was positive for myocardial ischemia in 22% of 82 patients initially classified as intermediate probability of acute myocardial infarction (AMI)/unstable angina (UA), and in 9% of 186 patients classified as low probability (P = 0.004)
Summary
Propranolol plasma levels and pharmacokinetics (PK) may be altered by cardiopulmonary bypass (CPB). The objective of our study was to assess the effect of different levels of airway pressure on lung morphology by performing a LRM during the lung CT-scan This way, we could set the best ventilatory strategy for the patient and identify the mechanisms involved during the LRM. The goal of this study was to determine the incidence of thrombocytopenia and the correlation with length of ICU stay, mortality rate, admission severity scores APACHE II and SAPS II, and multiple organ dysfunction scores SOFA and LODS. Multiple organ dysfunction has been recognized as a major factor associated with mortality in patients with acute respiratory failure (ARF). Purpose: The objectives of this study are (1) to describe demographics, clinical features, physiologic parameters, and prognosis of patients on mechanical ventilation admitted to the Intensive Care Unit of Hospital Moinhos de Vento; and (2) to identify predictors of mortality and ventilator time. Percutaneous access is an option in such patients, and the clinical staff can perform it
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