Abstract
The first known Ebola hemorrhagic fever (EHF) outbreak caused by Bundibugyo Ebola virus occurred in Bundibugyo District, Uganda, in 2007. Fifty-six cases of EHF were laboratory confirmed. Although signs and symptoms were largely nonspecific and similar to those of EHF outbreaks caused by Zaire and Sudan Ebola viruses, proportion of deaths among those infected was lower (≈40%).
Highlights
Ebola hemorrhagic fever (EHF) is a severe disease caused by several species of Ebolavirus (EBOV), in the family Filoviridae
After reports of a mysterious illness in Bundibugyo District, the presence of a novel, ¿fth EBOV virus species, Bundibugyo ebolavirus (BEBOV), was identi¿ed in diagnostic samples submitted to the Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, USA, in November 2007 [13]
Number of laboratory-con¿rmed Ebola hemorrhagic fever (EHF) cases diagnosed on the basis of positive acute-phase or convalescent-phase diagnostic samples and calculation of proportion of deaths among case-patients who had an acute-phase diagnostic sample, Bundibugyo District, Uganda, 2007
Summary
Ebola hemorrhagic fever (EHF) is a severe disease caused by several species of Ebolavirus (EBOV), in the family Filoviridae. Diagnostic samples from hospitalized patients with acute illness and community residents who had febrile illnesses and multiple additional signs, symptoms, or epidemiologic exposures suggestive of EHF, were routinely collected for EBOV testing. A laboratory-con¿rmed case of EHF was de¿ned as illness in a person whose diagnostic samples were found positive for EBOV infection by any of the following tests: PCR [13], virus isolation, antigen detection, or immunoglobulin (Ig) M ELISA [14,15].
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