Abstract
Savard et al.1 described a case of propofol-infusion syndrome (PRIS) heralding an occult case of mitochondrial disease. The authors stated: “Our observations support the recommendation to avoid using propofol in patients with known mitochondrial diseases.” Au contraire! In the practice of pediatric anesthesia, propofol (2–3 mg/kg) is primarily used as a single-dose induction agent, and sometimes in an infusion for surgical cases lasting a few hours. Recent reviews of anesthetic outcomes of patients with …
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