Prophylaxis of fungal infections in liver transplantation from donation after citizen's death

Abstract

As one of the commonest postoperative complications after liver transplantation, fungal infection has a high incidence and mortality. Nowadays, the development of the organ transplantation technique in China has already entered into the era of donation after citizen's death (DCD). Donors of DCD are mainly derived from the patients after brain death, cardiac death or death of both brain and cardiac. These donors usually suffer from long-term hypotension, ischemia, anoxia and secon-dary recessive or dominant infections during emergency treatment. Hence, preventing the fungal infections in donor organs and recipients after transplantation plays an important role in improving the success rate of liver transplantation. This review focuses on the clinical significance of preventing fungal infection in DCD of liver transplantation. Key words: Fungal infection; Liver transplantation; Risk factors; Prophylaxis