Abstract
BACKGROUND: Antibiotics are at times indiscriminately used in clinical management may cause adverse effects, drug resistance etc. Thus to optimize use, there is a need to regulate the prescription strategies with antimicrobial stewardship. MATERIAL & METHODS: To evaluate prophylaxis and post surgery uses of antibiotics with dose, route of administration, duration of antibiotic treatment, duration of stay in wards, no of antibiotics per prescription . This is a prospective observational type of study conducted as a collaboration of Santosh medical college Ghaziabad and All india institute of medical sciences Bhopal. Out of 169, 58(34.3%) were RESULTS: in orthopaedics (M/F = 37/21), and 111 in surgery (M/F = 57/75). In surgery, Beta lactam (amoxicillin/clavulanic acid, 84(49.7%) and ceftriaxone (79(46.7%) were given at dose of (mean dose1040 gram) for duration of 1.29 hours mean time. Post surgery the dose was 1052.97 g for 4.42 days . In orthopaedics Cefazolin of class cephalosporin was used in 31.4 % of cases at dose of (mean dose 999.13 g for mean duration of 4.19 days .Principle It was found cephalosporins (cefazolin and ceftriaxone) and beta lactam CONCLUSION: (amoxicillin/clavulanic acid) are preferred in orthopaedics and surgery respectively. This was as per the prescription norms and regulations.
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