Abstract
Clinical guidelines recommend prophylactic hydration to reduce the risk of contrast-induced nephropathy in high-risk patients, including those with chronic kidney disease. A recent single-center randomized trial showed no significant difference inthe incidence of contrast-induced nephropathy in ambulatory patients with stage3 chronic kidney disease who were randomized to no prophylactic hydration versusnormal saline hydration. While these results may identify patients who areless likely to benefit from prophylactic hydration, nephrologists and interventionalists should carefully consider the generalizability of these results toindividual patients.
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