Abstract
ABSTRACTPurpose Postoperative urinary retention (POUR) is one of the most common complications after surgical procedures under spinal anaesthesia. Recent studies have shown the beneficial effects of alpha-adrenergic blockers in preventing POUR. The aim of this prospective study was to investigate and compare the prophylactic effects of tamsulosin and alfuzosin on POUR after urologic surgical procedures under spinal anaesthesia.Materials and Methods A total of 180 males who underwent elective urologic surgery were included in this study. The patients were randomly allocated into three Groups. The Group I received placebo. Patients in Group II were given 0.4mg of tamsulosin orally 14 and 2 hours before surgery. Patients in Group III were given 10mg of alfuzosin ER orally 10 and 2 hours before surgery. All patients were closely followed for 24 hours postoperatively and their episodes of urinary retentions were recorded.Results There were 60 patients in each Group. Their mean age was 35.95±15.16 years. Fifteen patients in Group I (25%), 3 patients in Group II (5%) and 4 patients in Group III (6.7%) required catheterization because of urinary retention. In tamsulosin group and alfuzosin group, there were a significantly lower proportion of patients with POUR compared with the placebo Group (p=0.002 and p=0.006). The beneficial effects of tamsulosin and alfuzosin on POUR were similar between both Groups (p=0.697).Conclusion This study suggests that the use of prophylactic tamsulosin or alfuzosin can reduce the incidence of urinary retention and the need for catheterization after urologic surgical procedures under spinal anaesthesia.
Highlights
Spinal anaesthesia is a common regional anaesthesia technique performed by anaesthesiologists since 1898 [1]
Postoperative urinary retention (POUR) has generally been defined as the inability to pass any urine in the presence of a percussible or palpable bladder after surgery, but the definition varies ibju | Alpha-blockers on postoperative urinary retention after spinal anaesthesia widely
The beneficial effects of tamsulosin and alfuzosin on POUR were similar in both Groups (p=0.697) (Table-1)
Summary
Spinal anaesthesia is a common regional anaesthesia technique performed by anaesthesiologists since 1898 [1]. It has some complications such as hypotension, bradycardia, cardiac arrest, nausea-. A mainstay of initial management for patients with POUR, is associated with some complications and increases in cost of care [3, 4]. Both the health and financial costs of retention are considerable, because it can cause urinary tract infections and necessitate catheterization, which can in turn result in urethral strictures, prolonged hospital stays, and additional operations. Pharmacological therapy is viewed as an interesting option for patients developing urinary retention following surgery
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