Abstract
The technique of the double sucrose gap was used to perform voltage clamp experiments on small segments of isolated auricular trabeculae of the frog heart. The voltage dependence and kinetics of the delayed rectification current were analyzed. The total outward current could be dissociated into two components: one component is defined as leakage current (Il) and shows inward rectification; a second component is the delayed rectification current (IK). The activation ofIKcan be described by a Hodgkin and Huxley type of kinetical model. The rate constants are found to be smaller by a factor of about 103 than those described in the giant axon of the squid.
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