Abstract

The proposal of this research activity is to produce sol-gel-derived quaternary bioactive glass (SiO2–P2O5–CaO–Na2O) thin films, co-doped with europium and silver, by two different techniques, such as pulsed laser deposition (PLD) and spin coating (SC). A variety of methods were employed to assess the thermal, compositional, structural, and morphological characteristics of the samples: complex thermal analysis (TA), Fourier Transformed Infrared Spectroscopy (FTIR), X-ray diffraction (XRD), Scanning Electron Microscopy (SEM) coupled with Energy-dispersive X-ray Spectroscopy (EDS) were used to observe the quantitative and qualitative changes caused by the applied experimental parameters. Additionally, SBF immersion for bioactivity monitoring, and immunocytochemistry for substrate adhesion were used to evaluate the biological response of the deposited material, while antimicrobial activity was evaluated for a Gram-negative species, Escherichia coli.

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