Abstract
Novice carbon nanostructural material was investigated to estimate its integration to the bone tissue. Wedge osteotomy of a femur bone performed in experimental circumstance on 26 white rats (control=6, experiment=21). Wedge-shaped (h=4 mm, r=3 mm, α=12) implants were crafted from carbon nano-structural material and used to fill bone’s defect. Rats withdrove from the experiment in 3 months. Mechanical properties of the “bone-wedge-bone” block evaluated by the 3-point bending test. Field emission scanning electron microscope used to investigate biocomposite at the bone-to-implant border. The microelements distribution in the samples measured with energy dispersive X-ray analysis. Biomechanical properties of bone-to-implant biocomposite depend on clinical features of consolidation. Anyway, the toughness (T) of bone-to-implant zone is worse than bone-to-bone regenerate significantly (Tcontr = 56.97 MPa, Texp = 47.68 Mpa, Welsh p-value = 2.689e-07). No Ca, or P reveals in the body of implants. The quality and the thickness of the biocomposite on the bone-to-implant border predetermine clinical results of bone substitution. The absence of microelements inside the body of implants confirms that the implant structure is too subtle. Increasing porosity of material and creation of transverse channels can improve bone conduction and scaffold quality of carbon nano-implants.
Highlights
&DUERQH LPSODQWV KDYH PRUH WKDQ \HDUV KLVWRU\ RI DSSOLFDWLRQ LQ RUWKRSHGLF VXUJHU\ ,W VHHPV WKDW WKH QHZ JHQHUDWLRQ RI FDUERQ QDQRPDWHULDOV KDYH JRRG SURVSHFWV WR SURGXFH LPSODQWV IRU ERQH GHIHFWV VXEVWLWXWLRQ.
$EVWUDFW 1RYLFH FDUERQ QDQRVWUXFWXUDO PDWHULDO ZDV LQYHVWLJDWHG WR HVWLPDWH LWV LQWHJUDWLRQ WR WKH ERQH WLVVXH :HGJH RVWHRWRP\ RI D IHPXU ERQH SHUIRUPHG LQ H[SHULPHQWDO FLUFXPVWDQFH RQ ZKLWH UDWV FRQWURO H[SHULPHQW :HGJHVKDSHG K PP U PP Į LPSODQWV ZHUH FUDIWHG IURP FDUERQ QDQRVWUXFWXUDO PDWHULDO DQG XVHG WR ILOO ERQH
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
Summary
&DUERQH LPSODQWV KDYH PRUH WKDQ \HDUV KLVWRU\ RI DSSOLFDWLRQ LQ RUWKRSHGLF VXUJHU\ ,W VHHPV WKDW WKH QHZ JHQHUDWLRQ RI FDUERQ QDQRPDWHULDOV KDYH JRRG SURVSHFWV WR SURGXFH LPSODQWV IRU ERQH GHIHFWV VXEVWLWXWLRQ.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.