Abstract
Introduction: Full and fast restoration of cerebral blood flow in proximity to the initiation of intravenous tissue plasminogen activator (IV tPA) treatment occurs in 10 % of patients with acute ischemic stroke. This phenomenon is also known as effect. Lazarus pattern of cerebral blood vessel recanalization is attributed mainly to internal carotid artery and middle cerebral artery occlusions and is not frequent in basilar artery occlusions. Methods and Results: We present here a case of effect in patient with severe stroke due to occlusion of basilar artery treated with IV tPA more than three hours after the onset of stroke (190 minutes). Conclusion: Our case emphasizes the importance of treatment with IV tPA as initial one before the use of intraarterial tPA, in patients with total occlusion of main cerebral vessels, even in cases with relatively late initiation of treatment.
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