Abstract
(if average age≥70 and lower age limit≥55). Second, we searched the PubMed database for RCTs specifically designed for the elderly and published between January 2011 and January 2012, based on PubMed age categories and the above-mentioned age criteria.Main trial characteristics were extracted. Results.– From the random sample (n=339), 22 (6%) publications reported on RCTs specifically designed for the elderly. The second search yielded 305 publications on RCTs specifically designed for the elderly. Based on the trial characteristics, RCTs specifically designed for the elderly less frequently excludedparticipants based on upper age limits (P<0.001), more frequently focused on the cardiovascular and nervous system (P<0.001), and were more frequently performed in ahospital (P<0.001),when compared toRCTs not specifically designed for the elderly. Key conclusions.– Only a very small proportion of RCTs is specifically designed for the elderly. This proportion is even smaller than current literature illustrated.
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