Abstract

Univalent metal ions such as Na+, K+ and Cs+ can enhance not only the cyclization yields of some linear pentapeptides and heptapeptide but also their cyclization rates while some bivalent and trivalent metal ions such as Mg2+, Ca2+, Zn2+, Fe2+, Ni2+ and Cr3+ elevate neither the cyclization yields nor the cyclization rates and some of them prevent the cyclization.

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