Abstract
Promising recent regenerative medicine applications in plastic and reconstructive surgery
Highlights
Cosmetic and reconstructive surgery relies extensively on the complex relationship between skin, soft tissue and the underlying bone skeleton
The ability of adipose stem cells to rejuvenate by producing trophic factors, and to differentiate into different cell types, has provided promising utilization for a variety of different applications in plastic surgery [717]
The aim of this review is to summarize the recent patents in the nanotechnology field that carry some clinical significance in the treatment of soft tissue, that eventually may change the way we approach some reconstructive procedures [22,23]
Summary
Cosmetic and reconstructive surgery relies extensively on the complex relationship between skin, soft tissue and the underlying bone skeleton. Soft tissue loss and acquired soft tissue deficits are some of the daily challenges faced by the plastic surgeon. Traumatic and oncologic bone defects, and complex defects requiring vascular reconstruction are faced by plastic surgeons on a daily basis. Fat grafting has become one of the standard lines of care that has various applications in plastic surgery treatments [1,2,3,4,5,6]. Existing fat grafting methods are associated with reported side effects including infections [7,18], calcifications [19] and inconsistent resorption ratios in tissue [20]
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