Abstract

Prolonged QT syndrome is the most common genetic arrhythmia syndrome, and the majority of patients are undiagnosed. The syndrome is characterized by abnormally long ventricular repolarization (QT interval) on electrocardiogram, which may manifest as syncopal episodes, arrhythmias, or sudden death. Arrhythmias may be precipitated by stress or medications. There are few randomized controlled trials examining the safety of typical sedation medications in the patient with prolonged long-QT syndrome. This case describes the management of sedation in a patient with prolonged long-QT syndrome and then reviews the current literature regarding commonly utilized sedation medications.

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