Abstract
s1 April 1963Prolonged Erythroid Aplasia in Chronic Lymphocytic Leukemia: Favorable Response to Adrenocortical Steroids in Four Cases.J. D. Battle Jr., M.D., F.A.C.P., J. S. Hewlett, M.D., F.A.C.P., G. C. Hoffman, M.B.B.Chir.J. D. Battle Jr., M.D., F.A.C.P.Search for more papers by this author, J. S. Hewlett, M.D., F.A.C.P.Search for more papers by this author, G. C. Hoffman, M.B.B.Chir.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-58-4-731_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFive episodes of severe anemia and profound A reticulocytopenia associated with the virtual absence of erythroid precursors in the marrow lasting from 3 to 20 weeks were observed in 4 patients with chronic lymphocytic leukemia. A prompt resumption of erythropoiesis followed the administration of large doses of adrenocortical steroids in each patient. The direct Coombs test was positive in 2 patients, and in all 4 patients there was evidence of an active hemolytic process. Moderate hypogammaglobulinemia was present in 3 of the patients, and in one of these the administration of gamma globulin was followed by a significant but transient... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cleveland, Ohio (CI) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByAcquired pure red cell aplasia associated with chronic lymphocytic leukemiaPure Red Cell Aplasia 1 April 1963Volume 58, Issue 4Page: 731-732KeywordsAnemiaBone marrowChronic lymphocytic leukemiaErythropoiesisGlobulinsSteroids Issue Published: 1 April 1963 PDF DownloadLoading ...
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