Abstract

MYELOGRAPHY with metrizamide (Amipaque) is an increasingly popular technique useful in the evaluation of radiculopathy. The most common neurologic side effects are headache, nausea, vomiting, and dizziness.<sup>1-3</sup>More serious neuropsychiatric side effects reported include confusional states, hallucinations, sleep disturbances, agitation, and other signs of altered mental status.<sup>1-5</sup>These changes have been reported as brief, lasting less than 48 hours, and benign in outcome. We report a case, the first, to the best of our knowledge, in which the symptoms appearing after metrizamide myelography were severe and prolonged. A brief discussion of the etiology and treatment of these side effects follows the case presentation. <h3>Report of a Case</h3> A 56-year-old woman had a three-year history of low back and right leg pain precipitated by a minor injury. After an exacerbation of the pain that was not relieved by 14 days of bed rest, she was admitted to the hospital.

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