Abstract
Six patients in terminal chronic renal failure have been maintained on a program of prolonged (approximately twenty hour), periodic hemodialysis using the twin coil artificial kidney. Dialyses were conducted at six or seven day intervals. The patients were connected to the dialyzer by way of their indwelling, permanent Teflon A-V shunts. One patient has been maintained for seven months in a relatively good state of health. Five patients have been maintained for four months. Major complications encountered during sixty-five long dialyses were dehydration from excessive ultrafiltration, hypertension, convulsions and bleeding episodes. Complications encountered during the intervals between dialyses were dehydration, pulmonary congestion, hypertension, anemia and, rarely, hyperkalemia. At present, an important factor in continuing the dialysis program is maintenance of the Teflon A-V shunt, which may become thrombosed or may be jeopardized by an infected cutdown wound.
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